The volume and composition of body fluid compartments are strictly controlled. The differences in composition between the major body fluid compartments.
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Measurement of body fluid compartments pdf. Not interfere with body fluid distribution if the tracer is excreted in the urine then the loss can be determined and corrections made in the calculation. The size of tissue compartments in living man is best determined by dilution analysis. Ecw is under neuroendocrine control and the final regulation is accomplished by the kidney through retaining or excreting solutes and fluids. How to measure the volumes of body fluid compartments using marker substances. The distribution of water between the major body fluid compartments. Upon human body fluid changes that accompany a 21 day combined heat and exercise acclimation regime.
Total body water tbw extracellular fluid ecfv plasma volume pv interstitial fluid ifv intracellular water icw red cell volume rcv and blood volume bv. 18112012 14 copyright 2004 pearson education inc publishing as benjamin cummings. Body fluids 1 and 2 linda costanzo phd. Neonatology questions and controversies second edition 2012. Differently between body fluids and fat. Thus if a given concentration of a marker q is introduced into the body in a volume v.
Sinan canan created date. Endre sulyok md phd dsc in nephrology and fluidelectrolyte physiology. If the tracer is metabolised a series of measurements can be made and assuming exponential decline first order kinetics the volume of distribution can be determined by extrapolation back. The ratio of these compartments varies greatly between indi viduals and adjustment in dose may have to be made. Human fluid volumes may be subdivided into several compartments. After studying this lecture the student should understand.
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