Lung function is a relevant endpoint in pharmacological studies eg in models for asthma copd or infection in safety pharmacological studies performed according to the ich guideline s7a core battery part lung and follow up and finally in toxicological studies particularly if the airways are in the focus of interest. According to the avma guidelines which statement is true for the use of co2 as a euthanasia agent of mice.
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Which statement is true about body temperature measurement in rodents. 2 radiation is the transfer of heat from one object to another without direct contact. Among studies involving core and surface temperature measurements in mice the surface temperature is on average 257 c 34 c or 23 c lower than core temperature depending on the site. During the procedure mice should be monitored mainly for depth of anesthesia cardiovascular and respiratory function. Which statement is true about supporting body temperature in anesthetized rodents. Which statement is true regarding the radiation heat loss mechanism of the body. 3 radiation increases as the temperature difference between the objects decreases.
Many rodent studies have demonstrated different experimental outcomes due to differences in body temperature under anesthesia including studies of the heart brain liver and urogenital system. Which statement is true regarding care procedures for mice undergoing surgery. Which statement is true regarding care procedures for mice undergoing surgery. Lung function measurement techniques for rodents an overview. In investigations involving changes in body temperature in the rat 13 we have noted discrepanciess in the control levels and changes in response to given doses of drugs such as morphine. During the procedure mice should be monitored mainly for anesthesia body temperature and cardiovascular and respiratory function.
Maintaining body temperature eg via insulating materials and heating pads is an important objective of supportive care because rats may be unable to properly thermoregulate for some time after some procedures including anesthesia and surgery. Which statement is true about a records management system for clinical assessments of rodents. 16778595111119137 the technique used to measure body temperature is critical to the interpretation of an experiment due to the heterogeneity of temperature in different locations of the animals body ranging from the temperature of the tail to the animals true core temperature. Heat sources should be modulated to a safe temperature. 1 peripheral vasodilation minimizes radiant heat loss. General anesthesia causes disturbances of thermoregulation and other physiological functions.
Rectal probe thermometry is commonly used to measure body core temperature in rodents because of its ease of use. Although previous studies suggest that rectal measurement is stressful and results in long lasting elevations in body temperatures we evaluated how this procedure affects brain muscle skin and core temperatures measured with chronically implanted thermocouple electrodes in rats.
Gallery of Which Statement Is True About Body Temperature Measurement In Rodents
